“Fence of Madness” is a collaborative research project involving the University of Cagliari and the École Nationale Supérieure D’Architecture in Paris and Toulouse. Focusing on former psychiatric hospitals, Villa Clara in Cagliari and Rizzeddu in Sassari, the initiative aims to explore innovative possibilities for their reuse. In supporting this research with a documentary approach, we documented the two decommissioned complexes tracing the persistent characteristics of their original functions, the superimposed changes over time, and the elements indicative of their current adaptive reuse.